I've started watching the series Dead Like Me with Louise, and I'm enjoying it quite a bit. It reminds me of Wonderfalls a lot, though. Like Wonderfalls, it features a young female lead who, for reasons beyond her control or understanding, has been granted a bizarre supernatural, prescient power, and is now obligated to use it to help people. The lead in Wonderfalls is spoken to by inanimate objects who give her cryptic clues that can be used to help people around here. The lead in Dead Like Me is a grim reaper who is tasked with removing the souls from the bodies of the recently deceased, who will suffer incredible torment without her assistance. Both are sarcastic and sassy, and both shows are well-written and strangely funny.
I don't have much else to say at this point after just three episodes. But, if you liked Wonderfalls, I'm thinking you might want to check out Dead Like Me too.